Development of LAG-3/FGL1 blocking peptide and combination with radiotherapy for cancer immunotherapy
human anti-CD3 (OKT3, Biogems) and human anti-CD28 (CD28.2, Biogems) BioGems ; Acta Pharm Sin B. 2024 Mar;14(3):1150-1165. doi: 10.1016/j.apsb.2023.12.011. Epub 2023 Dec 19. Yuzhen Qian 1, Yixuan Sun 2, Peishang Shi 1, Xiuman Zhou 2, Qiongqiong Zhang 1, Qingyu Dong 2, Shengzhe Jin 1, Lu Qiu 1 2, Xiaoshuang Niu 2, Xiaowen Zhou 1, Wenshan Zhao 1, Yahong Wu 1 3, Wenjie Zhai 1 3, Yanfeng Gao 1 2 Affiliations expand Abstract Aside from antibodies, peptides show great potential as immune checkpoint inhibitors (ICIs) due to several …