Identifying Features of Cardiac Disease Phenotypes Based on Mechanical Function in a Catecholaminergic Polymorphic Ventricular Tachycardia Model
#Y27632/ROCK inhibitor (Biogems). Front Bioeng Biotechnol. 2022 May 10;10:873531. doi: 10.3389/fbioe.2022.873531. eCollection 2022. A Stempien 1 2, M Josvai 1 2, W J de Lange 3, J J Hernandez 3, J Notbohm 4, T J Kamp 5 6 7, H H Valdivia 5, L L Eckhardt 5 7, K R Maginot 3, J C Ralphe 3, W C Crone 1 2 4 Abstract Catecholaminergic polymorphic ventricular tachycardia (CPVT) is characterized by an arrhythmogenic mechanism involving disruption of calcium handling. This genetic disease can …