TGFβ promotes YAP-dependent AXL induction in mesenchymal-type lung cancer cells
https://pubmed.ncbi.nlm.nih.gov/33207077/ Mol Oncol. 2021 Feb;15(2):679-696. doi: 10.1002/1878-0261.12857. Epub 2020 Dec 5. Jeong-Yun Choi 1, Haeseung Lee 2, Eun-Ji Kwon 1, Hyeon-Joon Kong 1, Ok-Seon Kwon 3, Hyuk-Jin Cha 1 4Affiliations expand PMID: 33207077 PMCID: PMC7858114 DOI: 10.1002/1878-0261.12857 Abstract The acquisition of chemoresistance remains a major cause of cancer mortality due to the limited accessibility of targeted or immune therapies. However, given that severe alterations of molecular features during epithelial-to-mesenchymal transition (EMT) …
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