Insights into bioinformatic approaches for repurposing compounds as anti-viral drugs

Antivir Chem Chemother. Jan-Dec 2021;29:20402066211036822. doi: 10.1177/20402066211036822. Wenxiao Zheng 1 2 3, Leonardo D’Aiuto 1, Matthew J Demers 1, Vaishali Muralidaran 1, Joel A Wood 1, Maribeth Wesesky 1, Ansuman Chattopadhyay 4, Vishwajit L Nimgaonkar 1 5 6 PMID: 34463534 PMCID: PMC8411619 DOI: 10.1177/20402066211036822 Abstract Background: Drug repurposing is a cost-effective strategy to identify drugs with novel effects. We searched for drugs exhibiting inhibitory activity to Herpes Simplex virus 1 (HSV-1). Our strategy utilized gene expression data generated …

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