Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents
https://pubmed.ncbi.nlm.nih.gov/30183752/ PLoS One. 2018 Sep 5;13(9):e0203126. doi: 10.1371/journal.pone.0203126. eCollection 2018. Sheryl M Southard 1, Rama P Kotipatruni 1, William L Rust 1 PMID: 30183752 PMCID: PMC6124757 DOI: 10.1371/journal.pone.0203126 Abstract Induced pluripotent stem cell (iPSC) technology enables the creation and selection of pluripotent cells with specific genetic traits. This report describes a pluripotent cell line created specifically to form replacement pancreatic cells as a …