https://pubmed.ncbi.nlm.nih.gov/32990953/ Biotechnol Bioeng. 2021 Jan;118(1):442-452. doi: 10.1002/bit.27582. Epub 2020 Oct 13. B N Napiwocki 1 2, D Lang 3, A Stempien 1 2, J Zhang 3, R Vaidyanathan 3, J C Makielski 3, L L Eckhardt 3, A V Glukhov 3, T J Kamp 3 4, W C Crone 1 2 5 PMID: 32990953 PMCID: PMC8214444 DOI: 10.1002/bit.27582 Abstract Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have emerged as an exciting new tool for cardiac research and can serve as a preclinical platform …

Aligned human cardiac syncytium for in vitro analysis of electrical, structural, and mechanical readouts 더 보기 »

https://www.mdpi.com/2073-4409/11/6/951/htm?msclkid=2320efa7a69611ecbfb2e3ff4e60dc12 by Jyotsna Joshi 1,†,Bing Xu 1,2,†,Michael Rubart 3,Yun Chang 4,Xiaoping Bao 4,Hari P. Chaliki 1,Luis R. Scott 1 andWuqiang Zhu 1,5,6,* Cells2022, 11(6), 951; https://doi.org/10.3390/cells11060951Received: 24 February 2022 / Revised: 7 March 2022 / Accepted: 8 March 2022 / Published: 10 March 2022 Abstract Background: Cellular transplantation has emerged as promising approach for treating cardiac diseases. However, a poor engraftment rate limits our understanding on how transplanted cardiomyocytes contribute to cardiac function …

Optogenetic Control of Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Live Mice: A Proof-of-Concept Study 더 보기 »