MARK2 enhances cisplatin resistance via PI3K/AKT/NF-κB signaling pathway in osteosarcoma cells
Am J Transl Res. 2020 May 15;12(5):1807-1823. eCollection 2020. Xianfu Wei 1, Liang Xu 1 2, Salim Fa Jeddo 1, Ka Li 1, Xin Li 1, Jianmin Li 1 PMID: 32509178 PMCID: PMC7270034 Abstract Osteosarcoma is the most common primary bone malignancy found in children and young adults. Chemotherapy resistance, especially to cisplatin, presents a major clinical challenge in the treatment and prognosis of osteosarcoma. New biomarkers and mechanisms …