An aptamer-based drug delivery agent (CD133-apt-Dox) selectively and effectively kills liver cancer stem-like cells

댓글 달기 / Small Molecules / 글쓴이

Cancer Lett. 2021 Mar 31;501:124-132. doi: 10.1016/j.canlet.2020.12.022. Epub 2020 Dec 19. Gang Zhou 1, Sarah Da Won Bae 1, Romario Nguyen 1, Xiaoqi Huo 1, Shuanglin Han 1, Zhiqiang Zhang 2, Lionel Hebbard 3, Wei Duan 4, Mohammed Eslam 1, Christopher Liddle 1, Lawrence Yuen 5, Vincent Lam 5, Liang Qiao 6, Jacob George 7 PMID: 33352247 DOI: 10.1016/j.canlet.2020.12.022 Abstract Liver cancer has no effective therapies, hence a poor survival. Cancer stem-like cells not only contribute to cancer initiation and progression, but also to …

An aptamer-based drug delivery agent (CD133-apt-Dox) selectively and effectively kills liver cancer stem-like cells 더 보기 »

SETD7 mediates the vascular invasion in articular cartilage and chondrocytes apoptosis in osteoarthriis

댓글 달기 / Buffers and Solutions / 글쓴이

FASEB J. 2021 Mar;35(3):e21283. doi: 10.1096/fj.202000373RRRR. Jia Xiaoshi 1 2 3, Li Maoquan 1 2 3, Wang Jiwei 4, Ning Jinqiu 1 2 3, Zhao Ke 1 2 3 PMID: 33617050 DOI: 10.1096/fj.202000373RRRR Abstract The pathological characteristics of osteoarthritis are cartilage matrix degradation, chondrocytes apoptosis, and low-grade inflammation of the joint. Recent studies have shown that blood vessels grow from the subchondral bone to the articular cartilage. However, the relationship among inflammation, angiogenesis, and …

SETD7 mediates the vascular invasion in articular cartilage and chondrocytes apoptosis in osteoarthriis 더 보기 »

The involvement of insulin/ToR signaling pathway in reproductive performance of Rhodnius prolixus

댓글 달기 / Small Molecules / 글쓴이

Insect Biochem Mol Biol. 2021 Mar;130:103526. doi: 10.1016/j.ibmb.2021.103526. Epub 2021 Jan 13. Jimena Leyria 1, Ian Orchard 2, Angela B Lange 3 PMID: 33453353 DOI: 10.1016/j.ibmb.2021.103526 Abstract Insulins are peptide hormones widely studied for their important regulatory roles in metabolism, growth and development. In insects, insulin signaling along with the target of rapamycin (ToR) are involved in detecting and interpreting nutrient levels. …

The involvement of insulin/ToR signaling pathway in reproductive performance of Rhodnius prolixus 더 보기 »

Shopping Cart
Scroll to Top