A microfluidic platform to study the effects of GDNF on neuronal axon entrapment

Volume 308, 1 October 2018, Pages 183-191. Ze ZhongWangaMatthew D.WoodbSusan E.MackinnonbShelly E.Sakiyama-Elbertc https://doi.org/10.1016/j.jneumeth.2018.08.002 원본링크: https://www.sciencedirect.com/science/article/abs/pii/S0165027018302383?via%3Dihub Abstract Background One potential treatment strategy to enhance axon regeneration is transplanting Schwann Cells (SCs) that overexpress glial cell line-derived neurotrophic factor (GDNF). Unfortunately, constitutive GDNF overexpression in vivo can result in failure of regenerating axons to extend beyond the GDNF source, a …

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