Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids
Nat Commun . 2022 Mar 30;13(1):1692. doi: 10.1038/s41467-022-29279-4. Suran Kim # 1, Sungjin Min # 1, Yi Sun Choi 1, Sung-Hyun Jo 2, Jae Hun Jung 3, Kyusun Han 3, Jin Kim 1, Soohwan An 1, Yong Woo Ji 3 4, Yun-Gon Kim 2, Seung-Woo Cho 5 6 7 PMID: 35354790 / DOI: 10.1038/s41467-022-29279-4 Abstract Matrigel, a mouse tumor extracellular matrix protein mixture, is an indispensable component of most organoid tissue culture. However, it has limited the utility of organoids for drug development …