Genetic circuit design automation for the gut resident species Bacteroides thetaiotaomicron

Nat Biotechnol. 2020 Aug;38(8):962-969. doi: 10.1038/s41587-020-0468-5. Epub 2020 Mar 30. Mao Taketani 1 2, Jianbo Zhang 1, Shuyi Zhang 1, Alexander J Triassi 1, Yu-Ja Huang 1, Linda G Griffith 1, Christopher A Voigt 3Affiliations expand Erratum in Abstract Bacteroides thetaiotaomicron is a human-associated bacterium that holds promise for delivery of therapies in the gut microbiome1. Therapeutic bacteria would benefit from the ability to turn on different programs of gene …

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Gut metabolite trimethylamine N-oxide induces aging-associated phenotype of midbrain organoids for the induced pluripotent stem cell-based modeling of late-onset disease

# IWP2 (Biogems), #db-cAMP (Biogems) Front Aging Neurosci. 2022 Aug 16;14:925227. doi: 10.3389/fnagi.2022.925227. eCollection 2022 Youngsun Lee 1 2, Ji Su Kang 1 2, On-Ju Ham 1, Mi-Young Son 1 2, Mi-Ok Lee 1 2 Abstract Brain organoids are valuable research models for human development and disease since they mimic the various cell compositions and structures of the human brain; however, they have challenges in presenting aging phenotypes for …

Gut metabolite trimethylamine N-oxide induces aging-associated phenotype of midbrain organoids for the induced pluripotent stem cell-based modeling of late-onset disease 더 보기 »

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