Generation, genomic characterization, and differentiation of triploid human embryonic stem cells
#SB 431542; #LDN 193189; #3014193; #1066208; Guy Haim-Abadi 1, Tamar Golan-Lev 1, Amnon Koren 2, Nissim Benvenisty 3 Affiliations expand Free PMC article Abstract Humans are diploid organisms, and triploidy in human embryos is responsible for ∼10% of spontaneous miscarriages. Surprisingly, some pregnancies proceed to triploid newborns that suffer from many neuro-developmental disorders. To investigate the impact of triploidy on human development, we …