Mutant ANP induces mitochondrial and ion channel remodeling in a human iPSC-derived atrial fibrillation model
#dexamethasone (Biogems) JCI Insight. 2022 Apr 8;7(7):e155640. doi: 10.1172/jci.insight.155640. Olivia T Ly 1 2, Hanna Chen 1, Grace E Brown 2, Liang Hong 1, Xinge Wang 1 2, Yong Duk Han 2, Mahmud Arif Pavel 1, Arvind Sridhar 1 3, Mark Maienschein-Cline 4, Brandon Chalazan 1, Sang-Ging Ong 1 5, Khaled Abdelhady 6, Malek Massad 6, Lona Ernst Rizkallah 6, Jalees Rehman 1 2 6, Salman R Khetani 2, Dawood Darbar 1 2 3 6 Free PMC article Abstract Human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) can model heritable arrhythmias to personalize therapies for individual patients. Although …