Blood-based molecular and cellular biomarkers of early response to neoadjuvant PD-1 blockade in patients with non-small cell lung cancer

#anti-CD3 (Biogems, USA) ; #anti-CD28 (Biogems, USA) ; #BioGems International ; Cancer Cell Int 24, 225 (2024).  Cancer Cell International volume 24, Article number: 225 (2024) Cite this article Abstract Background Despite the improved survival observed in PD-1/PD-L1 blockade therapy, a substantial proportion of cancer patients, including those with non-small cell lung cancer (NSCLC), still lack a response. Methods Transcriptomic profiling …

Blood-based molecular and cellular biomarkers of early response to neoadjuvant PD-1 blockade in patients with non-small cell lung cancer 더 보기 »

A rare missense p.C125Y mutation in the TNFRSF1A gene identified in a Chinese family with tumor necrosis factor receptor-associated periodic fever syndrome

#Phorbol 12-myristate 13-acetate (PMA) ;  #1652981 ;  Front. Genet. 15:1413641. Qian M, Zhou J, Wu J, Zhang H, Yu S, Xu H, Yang Y, Zhou F, Yang Q, Shao L, Zhang W, Jiang N and Ruan Q. Background: Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is a rare autosomal dominant disorder with a low incidence in …

A rare missense p.C125Y mutation in the TNFRSF1A gene identified in a Chinese family with tumor necrosis factor receptor-associated periodic fever syndrome 더 보기 »

Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing

#CD105 (Biogems, USA) ; #CD73 (Biogems, USA) ; #BioGems International ; J Nanobiotechnology. 2024 Jun 26;22(1):373. Liming Wang 1, Jun Chen 1 2 3 4, Jia Song 1 2 3 4, Yingyue Xiang 1, Mengmeng Yang 1, Longqing Xia 1, Jingwen Yang 1, Xinguo Hou 1 2 3 4, Li Chen 5 6 7 8, Lingshu Wang 9 10 11 12 Affiliations expand Abstract Background: The use of stem cell-derived exosomes (Exos) as therapeutic vehicles is receiving increasing attention. Exosome administration has several advantages over cell transplantation, thus making exosomes promising …

Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing 더 보기 »

Expression of VISTA regulated via IFN-γ governs endogenous T-cell function and exhibits correlation with the efficacy of CD19 CAR-T cell treated B-malignant mice

#Anti-Mouse CD3 ; #Anti-Mouse CD28 ;  #05112 ; #10312 ;  J Immunother Cancer. 2024; 12(6): e008364. Donghai Tang 1, Li Zhao 1, Fen Yan 1, Chunxiao Ren 1, Kailin Xu 2 3, Kai Zhao 2 3 Affiliations expand Abstract Background: Despite continuous improvements in the new target and construction of chimeric antigen receptor (CAR)-T, relapse remains a significant challenge following CAR-T therapy. Tumor microenvironment (TME) strongly correlates with the efficacy …

Expression of VISTA regulated via IFN-γ governs endogenous T-cell function and exhibits correlation with the efficacy of CD19 CAR-T cell treated B-malignant mice 더 보기 »

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