ionomycin-10mg

Ionomycin Calcium Salt

Ionomycin Calcium Salt

Ionomycin은 Streptomyces conglobatus에서 발견된 세포 내 칼슘 연구에 사용되는 ionphore 입니다.   또한 IL-2, IL-4 및 perforin의 세포 내 생성을 자극하는 것으로 보고되었습니다.  보관이 용이한 칼슘염 형태로 공급됩니다.
카테고리:

Ionomycin Calcium Salt

Ionomycin은 Streptomyces conglobatus에서 발견된 세포 내 칼슘 연구에 사용되는 ionphore 입니다.
또한 IL-2, IL-4 및 perforin의 세포 내 생성을 자극하는 것으로 보고되었습니다.  보관이 용이한 칼슘염 형태로 공급됩니다.
SIZE 가격 (부가세별도) 제품번호
1mg
$35.00
5608212-1mg
10mg
$245.00
5608212-10mg
  • Preparation & Storage : Soluble in organic solvents such as ethanol or DMSO. DMSO up to 1.5 mg/ml  ( 2 mM ).  Product should be kept at -20°C.

  • Download TDS

 

[제품 인용 최신 논문]

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Catalog Number : 5608212
 product image

ADDITIONAL INFORMATION

Applications:
FA
Synonyms:
IONOMYCINCALCIUMSALT
Formulation:
Crystalline solid
Chemical Name:
calcium;(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-19,21-dihydroxy-22-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]-4,6,8,12,14,18,20-heptamethyl-11-oxido-9-oxodocosa-10,16-dienoate
Molecular Formula:

C41H70O9 Ca
Molecular Weight:
747.1
CAS Number
56092-82-1
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Liu, C. M., & Hermann, T. E. (1978). Characterization of ionomycin as a calcium ionophore. Journal of Biological Chemistry, 253(17), 5892-5894.

Morgan, A. J., & Jacob, R. (1994). Ionomycin enhances Ca2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane. Biochem. J, 300, 665-672.

Elzi, D. J., Bjornsen, A. J., MacKenzie, T., Wyman, T. H., & Silliman, C. C. (2001). Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils. American Journal of Physiology-Cell Physiology, 281(1), C350-C360.

 

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